Phosphodiesterases : CNS functions and diseases

• Other Authors: Zhang, Han-Ting, Xu, Ying, O'Donnell, James M.
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer, 2017.
• Series: Advances in neurobiology ; v. 17.
• Subjects: Phosphodiesterases.; Nervous system > Diseases > Molecular aspects.; elektronické knihy; electronic books
• ISBN: 9783319588117; 9783319588100; 9783319864792; 9783319588094
• Physical Description: 1 online resource

PDEs are a family of enzymes that catalyze the hydrolysis of intracellular cyclic neucleotides. They are implicated in a number of disorders and dysfunctions and PDE inhibitors have already proven to be effective therapies for erectile dysfunction, COPD, and psoriatic arthiritis. This family of enzy...