Type and Incidence of Soft Tissue Sarcomas in Korea: 2001-2007

• Published in: Journal of pathology and translational medicine pp. 557 - 563
• Main Authors: 최경운, 강혜윤, 구혜수, 권미선, 김동훈, 김미정, 김수진, 김영실, 김철환, 박용구, 박혜림, 백승삼, 유진영, 이안희, 이재혁, 이혜경, 장규윤, 주영채, 최준혁
• Format: Journal Article
• Language: English
• Published: 대한병리학회 01.12.2011
• Subjects: 병리학
• ISSN: 2383-7837; 2383-7845

Background: The Korean Bone and Soft Tissue Pathology Study Group of the Korean Society of Pathologists conducted a nationwide retrospective analysis of soft tissue sarcoma (STS) to pro-vide the clinicopathologic characteristics of STS within the population of the Republic of Korea. Methods: The cases of STS were collected during a 7-year period (2001-2007) from 19 institutes in Korea. All cases were classified according to the histologic criteria proposed by the World Health Organization. Clinicopathologic data were reviewed. Results: Data from 722 patients (median age, 50 years) were collected. Data showed a slight male predominance. The most frequent types of STS in decreasing order were liposarcoma, malignant fibrous histiocytoma, leiomyosarcoma, and synovial sarcoma. STS occurred throughout the body, although approximately half (47.8%) were located in the extremities. The majority of STS was histologically classified as high grade with a large tumor size (>5 cm). The overall survival rate for the patients was 76.3% (median follow-up time, 26 months; range, 1 to 89 months). Histologic grade, tumor size, American Joint Committee on Cancer stage, tumor site, and resection status were prognostic. Significant independent ad¬verse prognostic factors were large tumor size (>5 cm) and tumor site other than extremities. Conclusions: We reported the distribution and characteristics of STS in the Republic of Korea. KCI Citation Count: 1