Cerebral Gumma Mimicking a Brain Tumor in a Human Immunodeficiency Virus-Negative Patient: A Case Report1

• Published in: Journal of the Korean Society of Radiology pp. 181 - 185
• Main Authors: 백혜진, 김우진
• Format: Journal Article
• Language: English
• Published: 대한영상의학회 01.09.2013
• Subjects: 방사선과학
• ISSN: 2951-0805
• DOI: 10.3348/jksr.2013.69.3.181

Syphilis has a broad spectrum of clinical manifestations, and the cerebral gumma is a kind of neurosyphilis which is rare and can be cured by appropriate antibiotic treatments. However, in clinical practices, diagnosis of cerebral syphilitic gumma is often difficult because imaging and laboratory findings revealed elusive results. Herein, we present a rare case of neurosyphilis presenting as cerebral gumma confirmed by histopathological examination, and positive serologic and cerebrospinal fluid analyses. This case report suggests that cerebral gumma should be considered as possible diagnosis for human immunodeficiency virus-negative patients with space-occupying lesion of the brain. And this case also provides importance of clinical suspicions in diagnosing neurosyphilis because syphilis serology is not routinely tested on patients with neurologic symptoms. KCI Citation Count: 0