간헐적 정수압의 휴지기 길이가 세포의 부착력에 미치는 영향

• Published in: Biomaterials research pp. 223 - 227
• Main Authors: 신호준, 김인애, 이용재, 신정욱, 박수아, 이창훈, 조인희, 김영직
• Format: Journal Article
• Language: Korean
• Published: 한국생체재료학회 01.12.2004
• Subjects: 의공학
• ISSN: 1226-4601; 2055-7124

Cell adhesion to any material surface is considered to be fundamental and important phenomenon in the fields of tissue engineering. In this study, to investigate the changes in cell adhesive force due to resting time period during the intermittent hydrostatic pressurizing (IHP), cells were cultured under the IHP with various resting times. Then the cell adhesive forces were measured quantitatively utilizing a cell detachment test system. In the results, immediately after mechanical stimuli (150 minutes after seeding) and one hour later (210 minutes after seeding), the average adhesive force of experimental group 5 (resting time: 15min) compared with that of control group at same culture time was increased significantly (p<0.05). The results indicated that IHP can contribute in improving cell adhesive force and some of time intervals were required for the expression of cell response. KCI Citation Count: 0