위축성 위염과 장상피화생의 유병률 변화 및 위험인자의 변화: 다기관 연구 비교

• Published in: The Korean journal of helicobacter and upper gastrointestinal research pp. 247 - 257
• Main Authors: 황영재, 김나영, 김성은, 백광호, 이주엽, 박경식, 주영은, 명대성, 김현주, 송현주, 김흥업, 남광우, 신정은, 김현진, 김광하, 이종찬, 임선희, 서검석, 최석채
• Format: Journal Article
• Language: Korean
• Published: 대한상부위장관ㆍ헬리코박터학회 01.12.2018
• Subjects: 내과학
• ISSN: 1738-3331; 2671-826X
• DOI: 10.7704/kjhugr.2018.18.4.247

Background/Aims: The aim of this study was to analyze the trend of the prevalences of atrophic gastritis (AG) and intestinal metaplasia (IM) from 2011 to 2016∼2017 in Korea. And, the risk factors of AG and IM were compared between 2011 and 2016∼2017. Materials and Methods: A total of 4,023 subjects in 2011 and 2,506 subjects in 2016∼2017 were enrolled. AG and IM were diagnosed on the basis of endoscopic findings. Multivariate analysis was performed for risk factors of AG and IM. Seventeen factors were analyzed. Results: The seroprevalence of Helicobacter pylori decreased from 2011 (59.8%; 2,407/4,023) to 2016∼2017 (51.6%; 1,293/2,506; P＜0.001). The prevalence of AG decreased from 2011 to 2016∼2017 (P=0.018), but that of IM increased (P＜0.001). The risk factors of AG in 2011 were male sex, old age, H. pylori immuoglobulin G (IgG) positivity, family history of gastric cancer (GC), and high-salt diet. For IM in 2011, the risk factors were male sex, old age, H. pylori IgG positivity, and family history of GC. Risk factors of AG in 2016∼2017 were old age, H. pylori IgG positivity, and country of residence. For IM in 2016∼2017, the risk factors were male sex, old age, family history of GC, high fasting glucose level (≥126 mg/dL), H. pylori IgG positivity, and low income level. Conclusions: The difference in prevalence trends of AG and IM between 2016∼2017 and 2011 could be the result of the different risk factors of AG and IM, such as decreased prevalence of H. pylori infection. (Korean J Helicobacter Up Gastrointest Res 2018;18:247-257) KCI Citation Count: 1