黃連解毒湯·扁柏 정유 복합추출물의 항산화 및 항균활성에 관한 연구

• Published in: 대한본초학회지, 32(1) pp. 75 - 81
• Main Authors: 김보애, 박신호, 양재찬
• Format: Journal Article
• Language: Korean
• Published: 대한본초학회 01.01.2017
• Subjects: 한의학
• ISSN: 1229-1765; 2288-7199
• DOI: 10.6116/kjh.2017.32.1.75.

Objectives : The present study was designed to investigate effects of mixed extracts (9:1, v/v) of Hwangryunhaedok- tang, Chamaecyparis obtusa essential oil. We evaluated the antimicrobial and antioxidant activity by manufacturing mixed extracts as the materials for functional medicinal herb cosmetics. Methods : We performed antimicrobial were tested microbes (Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Candida albicans, Propionibacterium acnes) by disc diffusion method and measure clear zone. Antioxidant activities were measured by DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity. Results : Antimicrobial activities of mixed extracts against S. epidermideis, P. acnes, S. aureus, E. coli, and Candida. A were 10.9±3.0 ㎜, 16.9±2.0 ㎜, 9.2±2.0 ㎜, 10.3±1.0 ㎜, 11.8±3.0 ㎜ respectively. The Chamaecyparis obtusa essential oil had the highest antimicrobial activities against S. epidermideis, P. acnes, S. aureus, E. coli, and Candia. A and clear zone of microbes ware 16.7±3.0 ㎜, 28.8±0.2 ㎜, 15.9±2.0 ㎜, 11.5±1.0 ㎜, 16.3±3.0 ㎜. Hwangryunhaedok- tang extract showed antimicrobial activity but only P. acnes and S. aureus The antioxidant activities of the mixed extracts were tested through the evaluation of DPPH radical scavenging activity. The 100 % mixed extracts were found to have 90 % DPPH radical scavenging activity. The mixed extracts was presented similar antioxidant activities compared with that of ascorbic acid. As a result, A mixture extract is expected to have antimicrobial effects and free radical scavenging activity was found. Conclusions : Accordingly, It can be concluded that mixed extracts has the potential to cosmetic material. KCI Citation Count: 2