Infliximab으로 치료 받은 환자에서 발생한 결핵성 복막염과 동반된 Poncet’s Disease 1예

• Published in: Journal of rheumatic diseases pp. 55 - 59
• Main Authors: 박효, 박찬웅, 김기방, 이민지, 전석재, 심승철, 임미경, 신동혁
• Format: Journal Article
• Language: Korean
• Published: 대한류마티스학회 01.03.2011
• Subjects: 내과학
• ISSN: 2093-940X; 2233-4718

저자들은 infliximab치료를 받은 강직성척추염 환자에서유발된 결핵성 복막염을 진단받고 항결핵제를 복용중인38세 남자에서 발생한 다발성 관절염을 관찰하고 강직성척추염에 의한 말초 관절염과 결핵성 관절염을 감별하여Poncet’s disease로 진단하고 치료하여 증상의 호전을 보인증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Infliximab is a chimeric mouse/human monoclonal antibody against tumor necrosis factor-alpha (TNF-α) that is used worldwide to treat rheumatic disease. However, the reactivation of tuberculosis, including extrapulmonary menifestation,is a severe side effect of anti-TNF-α treatment. Mycobacterium tubercluosis causes two forms of joint involvement, TB arthritis and Poncet's disease. Poncet’s disease is a rare aseptic form of arthritis, known as reactive arthritis in tuberculosis. We encountered a case of tuberculous peritonitis with Poncet’s disease in a 38-yearold man with a history of ankylosing spondylitis that was treated with infliximab. We report this case with a review of the literature. KCI Citation Count: 3