EPITRANSCRIPTOMIC ANALYSIS OF GLIOMA

• Main Authors: OTERO, Jose, GIGLIO, Pierre, WANG, Wesley
• Format: Patent
• Language: English; French
• Published: 18.04.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The present disclosure relates to the field of epitranscriptomic signatures to determine glioma progression versus glioma pseudoprogression. Further, wherein identifying whether a subject has a progressive glioma or a pseudoprogressive glioma, the method comprising: a. isolating a tissue biopsy from the subject; b. detecting an altered N6-Methyladenosine (m6A) epigenetic modification on an mRNA from the tissue biopsy is disclosed. La présente divulgation concerne le domaine des signatures épitranscriptomiques pour déterminer la progression d'un gliome par rapport à une pseudo-progression de gliome.