DETECTION AND TREATMENT OF RESIDUAL DISEASE USING CIRCULATING TUMOR DNA ANALYSIS

The present disclosure provides a method of treating a cancer in a patient who has undergone a first anti-cancer therapy. Also provided is a method for monitoring treatment response and minimum residual disease in a neoadjuvantly treated cancer patient. Methods for primer design are also disclosed....

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Bibliographic Details
Main Authors ODENHEIMER, Ahuva, MURTAZA, Muhammed, CONTENTE-CUOMO, Tania, MCDONALD, Bradon
Format Patent
LanguageEnglish
Published 03.11.2022
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Summary:The present disclosure provides a method of treating a cancer in a patient who has undergone a first anti-cancer therapy. Also provided is a method for monitoring treatment response and minimum residual disease in a neoadjuvantly treated cancer patient. Methods for primer design are also disclosed. The present disclosure provides several tools for increasing the sensitivity and analytical precision of the disclosed methods for monitoring ctDNA.
Bibliography:Application Number: US202017621528