INFECTIOUS DISEASES

• Main Author: JUNG, DAVID HYUNWOOK
• Format: Patent
• Language: English; Korean
• Published: 11.05.2016
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TECHNICAL SUBJECTS COVERED BY FORMER USPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ARTCOLLECTIONS [XRACs] AND DIGESTS; VINEGAR; WINE

Infectious diseases cause 150 million deaths per year and threaten people. In order to improve the understanding of pathogenic bacteria, the present study was designed to redefine the relationship between human pathogenic bacteria and various environment colonies, such as prokaryotes, plants, and fungi, as well as the other bacteria, and research the interaction therebetween. The pathogenic bacteria were first homogenized and irradiated with gamma rays, and the half of the irradiated solution was sterilized by using a high-temperature high-pressure sterilizer. A total of nine organism species were used, including two species of plants, two species of fungi, one species of animal, and four species of microbes. The animals and fungi used in the study showed an inhibitory effect on pathogenic bacteria suspensions, but the plants showed a significant promotion effect. The other non-pathogenic prokaryotes and yeast were not affected. Through these results, the application of the bacterial pathogens to other eukaryotes or prokaryotes or the verification of mechanisms, in which these pathogens were maintained or developed, allows the insight of ecological statuses of human pathogenic bacteria and evolutionary relationships between pathogens and animals, plants, and fungi. Furthermore, the potential efficacy of these human pathogenic bacteria could be applied to the development of agricultural, environmental, and medical fields. From this study results, it is expected that new utility values of the human pathogenic bacteria can be found. 전염성 질병은 1년에 150만의 죽음을 초래하며 사람들을 위협한다. 본 연구는 병원성 세균에 대한 이해를 높이기 위해 인간 병원성 세균과 다른 세균은 물론 원핵생물, 식물, 균 등 다양한 환경 군집과의 관계를 재정의하고 상호작용을 연구하기 위해 설계되었다. 먼저, 병원성 세균을 균질화하고 감마선으로 조사하였으며, 조사된 용액의 반은 고온고압멸균기를 이용하여 멸균 처리했다. 총 9 종의 생물체가 사용되었는데, 2종의 식물, 2종의 균류, 1종의 동물, 4종의 미생물이 여기에 포함된다. 연구에 사용된 동물과 균류는 병원성 세균현탁액에 대해 억제효과를 보였지만, 식물들은 상당히 촉진되는 효과를 보였다. 다른 비병원성 원핵생물과 효모는 영향을 받지 않았다. 이 결과를 통해 세균성 병원체를 다른 진핵생물이나 원핵생물에 적용하거나, 이들 병원체가 유지되었거나 발달되어 온 기작을 확인하는 것은 인간 병원성 세균의 생태적 지위와 병원균과 동물, 식물, 균류와의 진화적 관계에 대한 통찰을 가능하게 한다. 더 나아가 이러한 인간 병원성 세균의 잠재적 효능을 농업, 환경, 의료 분야의 발전에 적용시킬 수도 있을 것이다. 본 연구 결과로 인간 병원성 세균의 새로운 효용가치를 찾을 수 있기를 기대한다.