METHODS OF TREATING WHSC1-OVEREXPRESSING CANCERS BY INHIBITING SETD2

The present disclosure provides methods and pharmaceutical compositions for treating or slowing the progression of cancers that overexpress the histone methyltransferase WHSC1, e.g., t(4; 14) multiple myeloma, by administering to a subject in need thereof a therapeutically effective amount of an inh...

Full description

Saved in:
Bibliographic Details
Main Authors TOTMAN, Jennifer, Anne, COSMOPOULOS, Katherine, Louise, THOMENIUS, Michael
Format Patent
LanguageEnglish
French
German
Published 06.10.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The present disclosure provides methods and pharmaceutical compositions for treating or slowing the progression of cancers that overexpress the histone methyltransferase WHSC1, e.g., t(4; 14) multiple myeloma, by administering to a subject in need thereof a therapeutically effective amount of an inhibitor of the histone methyltransferase, SETD2.
Bibliography:Application Number: EP20190889764