METHODS FOR TREATING ACTIVE EOSINOPHILIC ESOPHAGITIS

The present invention provides methods for treating, preventing or reducing the severity of active eosinophilic esophagitis. In certain embodiments, the present invention provides methods of increasing esophageal distensibility. The methods of the present invention comprise administering to a subjec...

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Bibliographic Details
Main Authors HAMILTON, Jennifer D, RADIN, Allen, MANNENT, Leda
Format Patent
LanguageEnglish
French
German
Published 10.06.2020
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides methods for treating, preventing or reducing the severity of active eosinophilic esophagitis. In certain embodiments, the present invention provides methods of increasing esophageal distensibility. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4/ interleukin-13 (IL-4/IL-13) pathway inhibitor such as an anti-IL-4R antibody.
Bibliography:Application Number: EP20180750578