华蟾毒它灵在制备抗结节性硬化症相关肾血管平滑肌脂肪瘤药物中的应用

• Format: Patent
• Language: Chinese
• Published: 22.07.2025
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

本发明属于生物医药技术领域，具体涉及华蟾毒它灵在制备抗结节性硬化症相关肾血管平滑肌脂肪瘤药物中的应用。所述华蟾毒它灵可直接抑制结节性硬化症相关肾血管平滑肌脂肪瘤细胞生长，提高结节性硬化症相关肾血管平滑肌脂肪瘤细胞凋亡标志物的蛋白表达水平，所述华蟾毒它灵可用于制备抗结节性硬化症相关肾血管平滑肌脂肪瘤药物，同时，华蟾毒它灵成本较低，为结节性硬化症相关肾血管平滑肌脂肪瘤的治疗提供了新的有效且低成本的潜在药物。 The invention belongs to the technical field of biological medicines, and particularly relates to application of cinobufotalin in preparation of a medicine for resisting renal vascular smooth muscle lipoma related to nodular sclerosis. The cinobufotalin can be used for directly inhibiting the growth of renal vascular smooth muscle lipoma cells related to the nodular sclerosis and improving the protein expression level of an apoptosis marker of the renal vascular smooth muscle lipoma cells related to the nodular sclerosis, and the cinobufotalin can be used for preparing the medicine for resisting the renal vascular smooth muscle lipoma cells related to the nodular sclerosis. Meanwhile, cinobufotalin is low in cost, and a novel, effective and low-cost potential medicine is provided for treatment of renal vascul