Application of SOCS3 as biomarker in preparation of hepatic failure prognosis prediction product and detection kit

• Main Authors: FAN YUCHEN, GAO SHUAI, WANG KAI, LI JIHUI, HAN LIYAN
• Format: Patent
• Language: Chinese; English
• Published: 09.02.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The invention relates to the technical field of biomedicine, in particular to application of SOCS3 as a biomarker in preparation of a hepatic failure prognosis prediction product and a detection kit. By detecting the methylation rate of the biomarker SOCS3, the hepatic failure survival prognosis of the subject can be predicted, a more timely clinical strategy is provided, and the limitation of the existing prediction method is also avoided. 本发明涉及生物医学技术领域，尤其涉及SOCS3作为生物标志物在制备肝衰竭预后预测产品中的应用及检测试剂盒。通过检测生物标志物SOCS3的甲基化率，可以对受试者肝衰竭生存预后进行预测，提供更加及时的临床策略，也避免了现有预测方法的局限性。