CIGB-300 for use in inducing anti-tumor and antiviral immunity

• Main Authors: VAZQUEZ BLOMQUIST, DAVID, M, BALLARDRON CASTRILLO IRENE CRISTINA, DIAZ REYES PABLO ANTONIO, PERERA NEGR ¨ AN, YASSER, AGUILAR NORIEGA DANIEL, PEREZ RODRIGUEZ SERGIO EDUARDO, LEMOS PEREZ GERARDO
• Format: Patent
• Language: Chinese; English
• Published: 27.10.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention relates to the use of a peptide identified as SEQ ID No: 1 for the preparation of a medicament for inducing anti-tumor and anti-viral immunity mediated by immunogenic cell death. The invention also provides a method for treating cancer or a viral infection, characterized in that a therapeutically effective amount of an agent comprising the synthetic peptide is administered to a subject in need thereof to induce anti-tumor and anti-viral immunity mediated by immunogenic cell death. A pharmaceutical combination comprising a peptide identified as SEQ ID No: 1 and a vaccine for cancer immunotherapy is also part of the invention, which achieves a more effective immunotherapeutic approach for this disease. 本发明涉及标识为SEQ ID No:1的肽在制备药剂中的用途，所述药剂用于诱导由免疫原性细胞死亡介导的抗肿瘤和抗病毒免疫。本发明还提供用于治疗癌症或病毒感染的方法，其特征在于，向有此需要的个体施用治疗有效量的药剂以诱导由免疫原性细胞死亡介导的抗肿瘤和抗病毒免疫，其中所述药剂包含所述合成肽。包含标识为SEQ IDNo:1的肽和用于癌症免疫疗法的疫苗的药学组合也是本发明的一部分，其取得该疾病的更有效的免疫治疗方法。