Anti-galectin 9 antibodies and their use in treatment of ocular melanoma

• Main Authors: ELENKO EVGENY, FILIPOVIC, ANITA, BOHLEN JOERG
• Format: Patent
• Language: Chinese; English
• Published: 19.09.2023
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A method for treating ocular melanoma, such as uveal melanoma, in a patient comprises administering to the patient an effective amount of an antibody that binds to galectin 9. Also provided herein are methods for identifying a subject as having an ocular melanoma based on a level of galectin 9 in a biological sample (e.g., a blood sample) from a subject suspected of having the ocular melanoma. 一种用于治疗患者的眼部黑素瘤例如葡萄膜黑素瘤的方法，包括向所述患者施用有效量的结合半乳糖凝集素9的抗体。本文还提供了用于基于来自疑似患有所述眼部黑素瘤的受试者的生物样品(例如，血液样品)中的半乳糖凝集素9水平将受试者鉴定为患有所述眼部黑素瘤的方法。