酪氨酸激酶2(TYK2)降解化合物和使用方法

本发明涉及杂双功能化合物(例如双功能小分子化合物)，含有一种或多种杂双功能化合物的组合物，以及在有需要的受试者中治疗某些疾病的使用方法。本发明还涉及鉴定这种杂双功能化合物的方法。 This disclosure relates to heterobifunctional compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the heterobifunctional compounds, and to methods of use the heterob...

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Bibliographic Details
Format Patent
LanguageChinese
Published 08.07.2025
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:本发明涉及杂双功能化合物(例如双功能小分子化合物)，含有一种或多种杂双功能化合物的组合物，以及在有需要的受试者中治疗某些疾病的使用方法。本发明还涉及鉴定这种杂双功能化合物的方法。 This disclosure relates to heterobifunctional compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the heterobifunctional compounds, and to methods of use the heterobifunctional compounds for the treatment of certain disease in a subject in need thereof. The disclosure also relates to methods for identifying such heterobifunctional compounds.
Bibliography:Application Number: CN20218076677