Dosing regimen for treating myelofibrosis and MPN-related conditions with NAVITOCLAX

• Main Authors: HORETH LUKAS, NUTALAPATI, SRIDHAR, HESLIP JAMES, MENSING SVEN
• Format: Patent
• Language: Chinese; English
• Published: 01.11.2022
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention described herein relates to a method of treating a human subject suffering from myelofibrosis or an MPN-related disorder, comprising administering to the subject naviitaclax, optionally in combination with rusotinib. 本文所述的发明涉及治疗患有骨髓纤维化或MPN相关病症的人类受试者的方法，包括向所述受试者施用任选地与鲁索替尼组合的navitoclax。