Derivation of somatotrophs from stem cells and uses thereof

The presently disclosed subject matter provides for in vitro methods of inducing differentiation of stem cells (e.g., human stem cells) into somatotrophs, and differentiated cells generated by such methods. The presently disclosed subject matter also provides for uses of such cells for treating grow...

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Bibliographic Details
Main Authors TABAR VIVIANE, PIAO JINGHUA
Format Patent
LanguageChinese
English
Published 21.08.2020
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The presently disclosed subject matter provides for in vitro methods of inducing differentiation of stem cells (e.g., human stem cells) into somatotrophs, and differentiated cells generated by such methods. The presently disclosed subject matter also provides for uses of such cells for treating growth hormone deficiency. 本发明公开的主题提供诱导干细胞(例如，人干细胞)分化为促生长激素细胞的体外方法，以及通过这些方法产生的分化细胞。本发明公开的主题还提供这些细胞用于治疗生长激素缺乏症的用途。
Bibliography:Application Number: CN201880085927