青光眼的治疗

本发明的实施方案总体上涉及一种硫酸葡聚糖或其药学上可接受的盐，所述硫酸葡聚糖或其药学上可接受的盐用于治疗、抑制或预防受试者的青光眼。所述实施方案的硫酸葡聚糖实现眼内压的降低和标准化，这是在保存视网膜神经节细胞和视网膜神经纤维层方面的神经保护作用，并且所述硫酸葡聚糖溶解已建立的小梁网瘢痕元素。 The present embodiments generally relate to dextran sulfate, or a pharmaceutically acceptable salt thereof, for use in treating, inhibiting or preventing...

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Bibliographic Details
Format Patent
LanguageChinese
Published 17.03.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:本发明的实施方案总体上涉及一种硫酸葡聚糖或其药学上可接受的盐，所述硫酸葡聚糖或其药学上可接受的盐用于治疗、抑制或预防受试者的青光眼。所述实施方案的硫酸葡聚糖实现眼内压的降低和标准化，这是在保存视网膜神经节细胞和视网膜神经纤维层方面的神经保护作用，并且所述硫酸葡聚糖溶解已建立的小梁网瘢痕元素。 The present embodiments generally relate to dextran sulfate, or a pharmaceutically acceptable salt thereof, for use in treating, inhibiting or preventing glaucoma in a subject. Dextran sulfate of the embodiments achieves a reduction and normalization of intraocular pressure, a neuroprotective effect in terms of preserving retinal ganglion cells and retinal nerve fiber layer and dissolves established trabecular meshwork scar elements.
Bibliography:Application Number: CN201880031854