种甲维盐的提纯方法

• Format: Patent
• Language: Chinese
• Published: 27.11.2018
• Subjects: CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; DERIVATIVES THEREOF; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; SUGARS; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE

本发明涉及种甲维盐的提纯方法，其工艺包括：首先将甲氨基阿维菌素提取液进行预处理，然后用大孔树脂吸附、二氯乙烷解析，所得解析液减压蒸馏去除二氯乙烷后加入乙酸异丙酯溶剂溶解，之后再加入氯化钠饱和溶液，充分搅拌，静置、分水、超滤膜过滤得到甲氨基阿维菌素精制液，将该精制液与苯甲酸溶液进行成盐反应即可。本发明利用大孔树脂纯化甲氨基阿维菌素提取液，使甲氨基阿维菌素与苯甲酸成盐反应产物甲维盐纯度达到90%以上，纯化后的甲氨基阿维菌素与苯甲酸成盐反应收率提高6%，提高产量，增加经济效益，本发明不用丙酮进行重结晶，减少溶媒损耗，降低溶媒回收能耗。 The invention relates to an emamectin benzoate purifying method which comprises the following steps: pretreating a methylamino abamectin extract; performing macroporous resin adsorption and dichloroethane analysis; performing reduced pressure distillation of the obtained analysis liquid to remove dichloroethane; adding an isopropyl acetate solution and dissolving; adding a sodium chloride saturated solution, and sufficiently stirring; standing, separating water and filtering with an ultrafiltration membrane to obtain methylamino abamectin refined liquid; and performing a salt forming reaction between the refined liquid and a benzoic acid solution. In the invention, the methylamino abamectin extract is purified by use of the macroporous resin, the