种小分子聚乙二醇的合成方法

• Format: Patent
• Language: Chinese
• Published: 17.08.2016
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; COMPOSITIONS BASED THEREON; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS; METALLURGY; ORGANIC CHEMISTRY; ORGANIC MACROMOLECULAR COMPOUNDS; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE; THEIR PREPARATION OR CHEMICAL WORKING-UP

本发明公开了种小分子聚乙二醇的合成方法。本发明研发了种新的聚乙二醇的制备工艺，采用二氢吡喃作保护基从单分子量的二聚体、三聚体、四聚体等低聚体聚乙二醇原料制备较大单分子量五聚体、六聚体、七聚体、八聚体，以致十二聚体、十六聚体、二十四聚体等。本发明制备方法简单、操作方便，适合工业化和批量生产。