Methods and compositions for maintaining the conformation and structural integrity of biomolecules

A composition includes a target pharmaceutical or biological agent, a solution containing the target pharmaceutical or biological agent, and substrate that is soluble in the solution. The substrate is capable of being solidified via a solidification process and the solidification process causes the...

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Main Authors Griffin, Nickolas B, Lynn Seifert, Jennifer, Crow, Brent B, Hubbard, Paul A, Patel, Alpeshkumar P, Nelson, Kevin D, Sood, Paul R
Format Patent
LanguageEnglish
Published 01.08.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A composition includes a target pharmaceutical or biological agent, a solution containing the target pharmaceutical or biological agent, and substrate that is soluble in the solution. The substrate is capable of being solidified via a solidification process and the solidification process causes the substrate to become physically or chemically cross-linked, vitrified, or crystallized. As a result of the solidification process, particles are formed. The target pharmaceutical or biological agent within the solution retains proper conformation to ultimately produce a desired effect.
Bibliography:Application Number: AU20220231694