Study on serum perfluoroalkyl and polyfluoroalkyl substances exposure status of community residents in Songjiang District， Shanghai

• Published in: Shanghai Yufang Yixue Vol. 35; no. 11; pp. 1081 - 1087
• Main Authors: LIANG Xinlei, DU Xiushuai, DU Zhiyuan, TAN Yajiao, BAI Xue, LI Zhou, ZHENG Weiwei, LI Jialing, YU Haiying, JIANG Lihua
• Format: Journal Article
• Language: Chinese
• Published: Shanghai Preventive Medicine Association 01.11.2023
• Subjects: correlation; influencing factor; internal exposure; perfluoroalkyl and polyfluoroalkyl substance; pollution characteristics
• ISSN: 1004-9231
• DOI: 10.19428/j.cnki.sjpm.2023.22887

ObjectiveTo investigate the characteristics of serum perfluoroalkyl substances （PFASs） exposure and potential influencing factors among community residents in Songjiang District， Shanghai.MethodsIn August 2021， residents who underwent routine health checkups in a community in Songjiang District， Shanghai were recruited as study subjects. The inclusion criteria were adult residents who had lived in the area for more than 3 years， had no occupational exposure history， no underlying diseases， were not pregnant， and were able to complete the questionnaire independently and sign the informed consent form. A questionnaire survey was conducted and venous blood samples were collected. The concentrations of 15 PFASs in serum were determined using ultra-high performance liquid chromatography-tandem quadrupole mass spectrometry （UPLC-MS/MS）. Ordered multi-class logistic regression， interquartile range （IQR）， and odds ratio （OR） were used to explore the influencing factors and risk magnitude of serum PFASs concentrations