Clinical efficacy of domino liver transplantation: An analysis of two cases

• Published in: 精准医学杂志 Vol. 39; no. 1; pp. 71 - 73
• Main Author: ZHANG Hui, WANG Jianhong, WANG Shuxian, FENG Shuai, LIU Jinquan, XU Xiangmei, DAI Deshu, SUN Shuang, XU Chuanshen
• Format: Journal Article
• Language: Chinese
• Published: Editorial Office of Journal of Precision Medicine 01.02.2024
• Subjects: liver transplantation|transplant recipients|living donors|treatment outcome|case reports
• ISSN: 2096-529X
• DOI: 10.13362/j.jpmed.202401018

Objective To investigate the clinical efficacy of domino liver transplantation (DLT) and to provide a refe-rence for expanding the sources of donor livers. Methods The clinical data of two cases who underwent DLT at our hospital in 2021 were collected, and a literature review was performed. Results Donor 1 was a healthy subject, recipient 1 (DLT donor) was a patient with ornithine transcarbamylase deficiency, and recipient 2 (DLT recipient) was a patient with Cirgler-Najiar syndrome. Donor 2 was a brain-dead donor as per the internationally standardized definitions, recipient 3 (DLT donor) was a patient with familial hypercholesterolemia, and recipient 4 (DLT recipient) was a patient with malignant liver tumor. After transplantation, all patients experienced recovery of their liver function in 1 week, and were discharged from the hospital after 2 to 4 weeks of hospitalization. Recipient 2 developed thrombosis in the left portal vein on day 4 after operation; after emergent thrombolysis and anticoagulant thera