Comparison of different preoperative decompression of biliary tract methods for patients with periampullary carcinoma complicated with obstructive jaundice

• Published in: Ji chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics Vol. 41; no. 7; pp. 1030 - 1034
• Main Author: CAO Hong-tao, ZHAO Bang-bo, ZHOU Xing-tong, WANG Yuan-yang, LI Tian-hao, QIN Cheng, WANG Wei-bin
• Format: Journal Article
• Language: Chinese
• Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College 01.07.2021
• Subjects: obstructive jaundice|percutaneous transhepatic cholangial drainage(ptcd)|endoscopic retrograde cholangiopancreatography(ercp)|pancreaticoduodenectomy
• ISSN: 1001-6325

Objective To investigate the efficacy of different methods in decompression of biliary tract(jaundice reduction) for patients with periampullary carcinoma combined with obstructive jaundice. Methods The clinical data of 128 patients with malignant jaundice treated by preoperative biliary decompression before pancreaticoduodenectomy were retrospectively analyzed in Peking Union Medical College Hospital from January 2015 to September 2020. Patients were divided into endoscopic retrograde cholangiopancreatography (ERCP) with stent placement group including 80 cases and percutaneous transhepatic cholangial drainage (PTCD) group including 48 cases according to different methods of jaundice reduction. Serological indicators including total bilirubin (TB) were monitored before jaundice reduction(TBpre) and surgery within one week respectively. The efficacy of jaundice reduction in two groups was compared and further categories were carried out according to the histological types. Results TB after jaundice reduction(