Analysis of risk factors of feeding intolerance in ICU patients with enteral nutrition (ICU肠内营养患者喂养不耐受的危险因素分析)

• Published in: 中西医结合护理 Vol. 10; no. 10; pp. 30 - 36
• Main Authors: LI Peiyao (李佩瑶), WANG Yue (王玥), ZHANG Yang (张洋), ZHANG Jinjuan (张金娟), JIA Dan (贾丹)
• Format: Journal Article
• Language: Chinese
• Published: Journal of International Translational Medicine Limited 01.10.2024
• Subjects: critical care; enteral nutrition; feeding intolerance; icu; icu患者; risk factor analysis; 危险因素分析; 喂养不耐受; 肠内营养支持; 重症护理
• ISSN: 2709-1961
• DOI: 10.55111/j.issn2709-1961.20240725004

Objective To investigate the risk factors of feeding intolerance in ICU patients with enteral nutrition. Methods Totally 504 ICU patients who received enteral nutrition support were selected and divided into tolerance group (n=331) and intolerance group (n=173) according to the symptoms of feeding intolerance. The general data, tolerance, enteral nutrition preparations, clinical treatment and drug application of the two groups were compared. Binary Logistic regression analysis was used to analyze the risk factors of feeding intolerance. Results The daily dosage of enteral nutrition preparations (OR=1. 007), time to start enteral nutrition (OR=7. 361), mechanical ventilation (OR=25. 643), vasoactive drugs (OR=19. 049), antibiotics (OR=23. 267), length of hospitalization (OR=1. 522), and acid-inhibiting drugs (OR=0. 149) were risk factors of feeding intolerance, and probiotics(OR=0. 016)was a protective factor of feeding intolerance. Conclusion The feeding intolerance of ICU patients is dependent on many factor