影响早产儿脑损伤的相关因素分析

目的 分析早产儿不同类型脑损伤的发生情况及影响因素。方法 收集239例早产儿的临床资料及头颅磁共振检查结果,分析产前、产时、产后因素对早产儿脑损伤的影响。结果 早产儿脑损伤的发生率为25.5%,其中出血性脑损伤占10.5%,缺血性脑损伤占10.5%,出血＋缺血性脑损伤占4.6%。胎龄越小,出血性脑损伤及总脑损伤发生率越高（P〈0.01）,缺血性脑损伤及出血＋缺血性脑损伤的发生率与胎龄无关（P〉0.05）。出血性、缺血性及总脑损伤发生率均与出生体重无关（P〉0.05）。胎龄〈34周早产儿脑损伤的保护因素是经产（OR=0.292,95%CI：0.088~0.972）和剖宫产（OR=0.075,95...

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Published in中国当代儿科杂志 Vol. 18; no. 6; pp. 471 - 475
Main Author 马力 温晓红 杨海波 黄金华 陈楠
Format Journal Article
LanguageChinese
Published 2016
Subjects
危险因素
回顾性研究
多因素分析
早产儿
脑损伤
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ISSN1008-8830

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Summary:目的 分析早产儿不同类型脑损伤的发生情况及影响因素。方法 收集239例早产儿的临床资料及头颅磁共振检查结果,分析产前、产时、产后因素对早产儿脑损伤的影响。结果 早产儿脑损伤的发生率为25.5%,其中出血性脑损伤占10.5%,缺血性脑损伤占10.5%,出血＋缺血性脑损伤占4.6%。胎龄越小,出血性脑损伤及总脑损伤发生率越高（P〈0.01）,缺血性脑损伤及出血＋缺血性脑损伤的发生率与胎龄无关（P〉0.05）。出血性、缺血性及总脑损伤发生率均与出生体重无关（P〉0.05）。胎龄〈34周早产儿脑损伤的保护因素是经产（OR=0.292,95%CI：0.088~0.972）和剖宫产（OR=0.075,95%CI：0.015~0.368）;胎龄≥34周早产儿脑损伤的保护因素是剖宫产（OR=0.296,95%CI：0.131~0.672）,危险因素是严重感染（OR=8.176,95%CI：1.202~55.617）。结论 在临床工作中,应尽量延长早产儿的胎龄、掌握剖宫产指征,积极有效地预防及治疗感染,以期预防或减少早产儿脑损伤的发生。
Bibliography:Brain injury; Retrospective study; Risk factor; Multivariate analysis; Preterm infant
43-1301/R
MA Li, WEN Xiao-Hong, YANG Hai-Bo, HUANG Jin-Hua, CHEN Nan. （Department of Pediatrics, Third Affiliated Hospital of Anhui Medical University, Hefei 230061, China ）
ObjectiveTo investigate the incidence of different types of brain injury in preterm infants and their inlfuencing factors.MethodsThe clinical data and head magnetic resonance imaging （MRI） ifndings of 239 preterm infants were collected, and the inlfuence of antepartum, intrapartum, and postpartum factors on brain injury in preterm infants was analyzed.ResultsThe incidence rate of brain injury in preterm infants was 25.5%; among these infants, 10.5% had hemorrhagic brain injury, 10.5% had ischemic brain injury, and 4.6% and hemorrhagic and ischemic brain injury. The infants with a lower gestational age had higher incidence rates of hemorrhagic brain injury and overall brain injury （P〈0.01）. The incidence rates of ischemic brain injury and hemorrhagic and isc
ISSN:1008-8830