Disorders of Bone Mineral Metabolism in Chronic Kidney Disease

In children with chronic kidney disease (CKD) optimal control of bone and mineral homeostasis is essential not only for the prevention of debilitating skeletal complications and for achieving adequate growth but also for preserving long-term cardiovascular health. As the growing skeleton is highly d...

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Bibliographic Details
Published inPediatric Kidney Disease pp. 1533 - 1566
Main Authors Schmitt, Claus P., Shroff, Rukshana
Format Book Chapter
LanguageEnglish
Published Berlin, Heidelberg Springer Berlin Heidelberg 2016
Subjects
Calcifications
Calcimimetic compound
Children
Hyperpatathyroidism
One imaging
Phosphate binder
Renal osteodystrophy
Vitamin D
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ISBN9783662529706
366252970X
DOI10.1007/978-3-662-52972-0_58

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Summary:In children with chronic kidney disease (CKD) optimal control of bone and mineral homeostasis is essential not only for the prevention of debilitating skeletal complications and for achieving adequate growth but also for preserving long-term cardiovascular health. As the growing skeleton is highly dynamic and at particular risk of deterioration, close control of bone and mineral homeostasis is required. The chapter gives a detailed overview on the pathogenic mechanisms involved in CKD-MBD, on the prospects and limitations of current biochemical and radiological diagnostic tools and on established and new therapeutic means. Therapeutic algorithms are given based on recent pediatric guidelines.
ISBN:9783662529706
366252970X
DOI:10.1007/978-3-662-52972-0_58