Fisiopatologia dell’ipertensione portale e della ritenzione idrosalina nella cirrosi

Portal hypertension is caused by an increased resistance to portal outflow and an increased portal blood inflow. Portal hypertension is associated with an abnormal distribution of the blood volume, which is increased in the splanchnic territory and reduced in the non-splanchnic compartments. The rel...

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Bibliographic Details
Published inRecenti Progressi in Medicina Vol. 102; no. 3; pp. 134 - 140
Main Authors Giovanni Garini, Marco Delsante, Francesco Iannuzzella
Format Journal Article
LanguageItalian
Published Il Pensiero Scientifico Editore 01.03.2011
Subjects
ascite
Cirrosi epatica
sodium and water retention
portal hypertension
vasodilatazione splancnica
ritenzione idro-salina
ipertensione portale
Ascites
liver cirrhosis
splanchnic vasodilatation
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ISSN0034-1193
2038-1840
DOI10.1701/608.7070

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Summary:Portal hypertension is caused by an increased resistance to portal outflow and an increased portal blood inflow. Portal hypertension is associated with an abnormal distribution of the blood volume, which is increased in the splanchnic territory and reduced in the non-splanchnic compartments. The relative underfilling of the arterial circulation is responsible for the sodium and water retention, which is a consequence of the baroceptor-mediated activation of vasoconstrictor and antinatriuretic factors triggered to restore circulatory integrity.
ISSN:0034-1193
2038-1840
DOI:10.1701/608.7070