An enhanced deep image model for glaucoma diagnosis using feature-based detection in retinal fundus

• Published in: Medical & biological engineering & computing Vol. 59; no. 2; pp. 333 - 353
• Main Authors: Singh, Law Kumar, Pooja, Garg, Hitendra, Khanna, Munish, Bhadoria, Robin Singh
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2021; Springer Nature B.V
• Subjects: Algorithms; Bayesian analysis; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Biomedicine; Computer Applications; Diagnosis; Feature extraction; Glaucoma; Human Physiology; Image analysis; Image enhancement; Image processing; Imaging; Learning algorithms; Machine learning; Medical diagnosis; Original Article; Radiology; Retina; Support vector machines; Glaucoma diagnosis; Retinal fundus image; Cup-to-disc ratio; Inferior superior nasal temporal (ISNT) regions; Machine learning
• ISSN: 0140-0118; 1741-0444; 1741-0444
• DOI: 10.1007/s11517-020-02307-5

This paper proposes a deep image analysis–based model for glaucoma diagnosis that uses several features to detect the formation of glaucoma in retinal fundus. These features are combined with most extracted parameters like inferior, superior, nasal, and temporal region area, and cup-to-disc ratio that overall forms a deep image analysis. This proposed model is exercised to investigate the various aspects related to the prediction of glaucoma in retinal fundus images that help the ophthalmologist in making better decisions for the human eye. The proposed model is presented with the combination of four machine learning algorithms that provide the classification accuracy of 98.60% while other existing models like support vector machine (SVM), K-nearest neighbors (KNN), and Naïve Bayes provide individually with accuracies of 97.61%, 90.47%, and 95.23% respectively. These results clearly demonstrate that this proposed model offers the best methodology to an early diagnosis of glaucoma in retinal fundus. Graphical abstract