New mechanical recanalization devices - the future in pediatric stroke treatment?

• Published in: The Journal of invasive cardiology Vol. 22; no. 2; p. 63
• Main Authors: Grunwald, Iris Quasar, Walter, Silke, Shamdeen, Mohammed Ghiath, Dautermann, Anna, Roth, Christian, Haass, Anton, Bolar, Linet Jenifa, Reith, Wolfgang, Kühn, Anna Luisa, Papanagiotou, Panagiotis
• Format: Journal Article
• Language: English
• Published: United States 01.02.2010
• Subjects: Acute Disease; Adolescent; Angiography, Digital Subtraction; Basilar Artery - diagnostic imaging; Brain Ischemia - diagnostic imaging; Brain Ischemia - surgery; Carotid Arteries - diagnostic imaging; Catheterization; Cerebral Angiography; Child; Female; Humans; Male; Stroke - diagnostic imaging; Stroke - surgery; Thrombectomy - instrumentation; Thrombectomy - methods; Thrombectomy - trends; Vacuum Curettage - instrumentation; Vacuum Curettage - methods; Vacuum Curettage - trends
• ISSN: 1557-2501; 1557-2501

To evaluate the recanalization rate and clinical outcome in children with acute ischemic stroke following treatment with innovative mechanical thrombectomy devices. Three subjects aged 7-16 years presenting with acute cerebral vascular occlusions (thrombolysis in myocardial infarction [TIMI] 0) were treated with either the Penumbra System, operating on an aspiration platform, or the Phenox clot retriever device, a flexible wire compound with perpendicularly-oriented polyamid microfilaments. Target vessels were the internal carotid artery, the middle cerebral artery and the basilar artery. Successful recanalization (TIMI 3) was attained in all cases. No device-related complications or intracranial hemorrhage occurred. Follow up was conducted for up to 30 days. A 10- to 26-point improvement in the National Institutes of Health Stroke Scale (NIHSS) score was achieved. Mechanical thrombectomy devices possess a dual advantage whereby they can achieve instant recanalization as well as minimize the number of bleeds that customarily accompany intravenous and intra-arterial therapy. These new devices could contribute greatly to treatment decisions in a field not yet clearly defined by current guidelines.