Opsoclonus myoclonus syndrome: Response to plasmapheresis

An 18-month-old with idiopathic opsomyoclonus, refractory to therapy with ACTH, corticosteroids, and clonazepam received plasmapheresis along with oral corticosteroids and azathioprine. The subject improved dramatically following this treatment. Anticerebellar antibodies were detected from the plasm...

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Published inIndian pediatrics Vol. 41; no. 5; pp. 499 - 502
Main Authors SHEELA, S. R, MANI, P. J
Format Journal Article
LanguageEnglish
Published New Delhi Indian Pediatrics 01.05.2004
Subjects
Biological and medical sciences
Child, Preschool
Female
General aspects
Humans
Infant
Male
Medical sciences
Nervous system (semeiology, syndromes)
Nervous system as a whole
Neurology
Oculomotor disorders
Ophthalmology
Paraneoplastic Syndromes, Nervous System - therapy
Plasmapheresis
Asia
India
Human
Pediatrics
Nervous system diseases
Myoclonus
Opsoclonus
Infant
Involuntary movement
Plasmapheresis
Case study
Eye disease
Treatment
Tropical medicine
Oculomotor syndrome
Neurological disorder
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ISSN0019-6061

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Summary:An 18-month-old with idiopathic opsomyoclonus, refractory to therapy with ACTH, corticosteroids, and clonazepam received plasmapheresis along with oral corticosteroids and azathioprine. The subject improved dramatically following this treatment. Anticerebellar antibodies were detected from the plasma in this patient and in a two and a half year-old girl with cerebellar ataxia secondary to an adrenal ganglioneuroma.
Bibliography:ObjectType-Case Study-2
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ISSN:0019-6061