The evaluation of the inhibition of the macrophage migration inhibition test with the polysaccharid antigen "C" of Taenia saginata in human taeniasis (author's transl)

• Published in: Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie Vol. 240; no. 4; p. 538
• Main Authors: Boroń-Kaczmarska, A, Machnicka-Roguska, B, Lotocka, K, Sokolewicz-Bobrowska, E
• Format: Journal Article
• Language: German
• Published: Germany 01.06.1978
• Subjects: Adult; Cell Migration Inhibition; Diagnosis, Differential; Humans; Hypersensitivity, Delayed; Macrophages - immunology; Middle Aged; Polysaccharides, Bacterial - immunology; Taenia - immunology; Taeniasis - diagnosis; Taeniasis - immunology
• ISSN: 0300-9688

The statistical analysis of results of the leukocyte migration inhibition test with polysaccharide antigen C of T. saginata in 49 patients with taeniasis and 20 healthy persons was performed. Examinations took place in two series: before medication (series I) and 7 days after treatment (series II). In the first series, a significant decrease in the migration index (0.42) was found in the patients' group as compared with that of the control group (0.92). In the second series, the migration index was subject to an increase (0.62) which, however, did not reach the value obtained in the control group. In both series, statistically significant differences in the indices of the test performed were observed between patients and the control group of healthy individuals. The results obtained in the present studies demonstrate that T. saginata invasion in human brings about the development of a cellular hypersensitivity reaction of delayed type which is revealed in the leukocyte migration inhibition test; the elimination of the parasite leads to an impairment of the effect of this reaction within a relatively short period.