肝细胞癌微创与多学科综合诊疗——2018广州共识
摘要:中国绝大多数肝癌是乙型病毒性肝炎和肝硬化长期发展的结果,具有富血供、多中心起源特点,早期即可侵犯门静脉小分支并发生肝内转移。因此,肝癌发生之初即是一种局部器官及全身性疾病。为此,临床上需要采用包括局部治疗 (如手术切除、射频消融、微波消融、化学消融、冷冻消融等) 、器官水平治疗[如经导管动脉灌注化疗、经肝动脉化疗栓塞术 (TACE) ]和系统治疗 (如免疫治疗、抗病毒治疗、分子靶向治疗等) 在内的综合治疗方案。本共识阐述肝细胞癌微创与多学科综合诊断和治疗方法,凸显八大特点: (1) 肝动脉造影、肝动脉造影CT、动脉-门静脉造影CT、碘化油CT、TACE-CT有助于发现更多子灶,精确分期;...
Saved in:
| Published in | Linchuang gandanbing zazhi Vol. 35; no. 10; pp. 2176 - 2184 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
Changchun
Journal of Clinical Hepatology
01.10.2019
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 1001-5256 2097-3497 |
| DOI | 10.3969/j.issn.1001-5256.2019.10.009 |
Cover
| Abstract | 摘要:中国绝大多数肝癌是乙型病毒性肝炎和肝硬化长期发展的结果,具有富血供、多中心起源特点,早期即可侵犯门静脉小分支并发生肝内转移。因此,肝癌发生之初即是一种局部器官及全身性疾病。为此,临床上需要采用包括局部治疗 (如手术切除、射频消融、微波消融、化学消融、冷冻消融等) 、器官水平治疗[如经导管动脉灌注化疗、经肝动脉化疗栓塞术 (TACE) ]和系统治疗 (如免疫治疗、抗病毒治疗、分子靶向治疗等) 在内的综合治疗方案。本共识阐述肝细胞癌微创与多学科综合诊断和治疗方法,凸显八大特点: (1) 肝动脉造影、肝动脉造影CT、动脉-门静脉造影CT、碘化油CT、TACE-CT有助于发现更多子灶,精确分期; (2) TACE/消融作为早期肝癌首选治疗; (3) 浸润型肝癌作为独立分型; (4) 微创综合治疗转移淋巴结; (5) M (转移) 分期细化用于指导个体化治疗和判断预后; (6) 肝癌伴肝功能严重失代偿是肝移植候选标准; (7) 提倡生物免疫、中医中药、抗病毒及社会心理治疗贯穿各期治疗方案; (8) 建议开展早、中期肝癌微创介入治疗与外科手术多中心随机对照试验研究。 |
|---|---|
| AbstractList | R735.7; 中国绝大多数肝癌是乙型病毒性肝炎和肝硬化长期发展的结果,具有富血供、多中心起源特点,早期即可侵犯门静脉小分支并发生肝内转移.因此,肝癌发生之初即是一种局部器官及全身性疾病.为此,临床上需要采用包括局部治疗(如手术切除、射频消融、微波消融、化学消融、冷冻消融等)、器官水平治疗[如经导管动脉灌注化疗、经肝动脉化疗栓塞术(TACE)]和系统治疗(如免疫治疗、抗病毒治疗、分子靶向治疗等)在内的综合治疗方案.本共识阐述肝细胞癌微创与多学科综合诊断和治疗方法,凸显八大特点:(1)肝动脉造影、肝动脉造影CT、动脉-门静脉造影CT、碘化油CT、TACE-CT有助于发现更多子灶,精确分期;(2)TA-CE/消融作为早期肝癌首选治疗;(3)浸润型肝癌作为独立分型;(4)微创综合治疗转移淋巴结;(5)M(转移)分期细化用于指导个体化治疗和判断预后;(6)肝癌伴肝功能严重失代偿是肝移植候选标准;(7)提倡生物免疫、中医中药、抗病毒及社会心理治疗贯穿各期治疗方案;(8)建议开展早、中期肝癌微创介入治疗与外科手术多中心随机对照试验研究. 摘要:中国绝大多数肝癌是乙型病毒性肝炎和肝硬化长期发展的结果,具有富血供、多中心起源特点,早期即可侵犯门静脉小分支并发生肝内转移。因此,肝癌发生之初即是一种局部器官及全身性疾病。为此,临床上需要采用包括局部治疗 (如手术切除、射频消融、微波消融、化学消融、冷冻消融等) 、器官水平治疗[如经导管动脉灌注化疗、经肝动脉化疗栓塞术 (TACE) ]和系统治疗 (如免疫治疗、抗病毒治疗、分子靶向治疗等) 在内的综合治疗方案。本共识阐述肝细胞癌微创与多学科综合诊断和治疗方法,凸显八大特点: (1) 肝动脉造影、肝动脉造影CT、动脉-门静脉造影CT、碘化油CT、TACE-CT有助于发现更多子灶,精确分期; (2) TACE/消融作为早期肝癌首选治疗; (3) 浸润型肝癌作为独立分型; (4) 微创综合治疗转移淋巴结; (5) M (转移) 分期细化用于指导个体化治疗和判断预后; (6) 肝癌伴肝功能严重失代偿是肝移植候选标准; (7) 提倡生物免疫、中医中药、抗病毒及社会心理治疗贯穿各期治疗方案; (8) 建议开展早、中期肝癌微创介入治疗与外科手术多中心随机对照试验研究。 |
| Author | 亚太影像引导下肿瘤微创治疗协会,中国抗癌协会肿瘤微创治疗专业委员会，亚洲肿瘤消融学会（2017） |
| Author_xml | – sequence: 1 fullname: 亚太影像引导下肿瘤微创治疗协会,中国抗癌协会肿瘤微创治疗专业委员会，亚洲肿瘤消融学会（2017） |
| BookMark | eNpFj81Kw0AcxBepYK19Cj14SfzvZ7I3pWgVCl70XDbpprSUtDYWoSdRLEVEFERRsSfRkxZPKhV9F3FJHsNIRWFgGPgxw0yjTNgMNUJzGGwqhVyo27UoCm0MgC1OuLAJYJlGG0BOoCwB6ViUSSeDsn_MFMpHUc0DjqmQjIssWkz2buJRL9kfxJdH5v3R9K-_Xo7N7ZV5uIvvT-PRmznpJ8PD-Pzic_csVbrimtcP8zwwB0_JsDeDJgPViHT-13Noc2V5o7BqldaLa4WlktXCFEuLcqGBBp6jiKe15Fp5PvEZcM4keL4WQgTadSqO4JyC61Z8gZkKFODA0wFxaA7Nj3t3VBiosFquNzvtMF0sN_xqxet2f-6nR0Gm6OwYbbWbWx0dbf-zlDAgkmHG6Df1kXJz |
| ClassificationCodes | R735.7 |
| ContentType | Journal Article |
| Copyright | 2019. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
| Copyright_xml | – notice: 2019. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
| DBID | 3V. 7X7 7XB 88E 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH K9. M0S M1P PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI 2B. 4A8 92I 93N PSX TCJ |
| DOI | 10.3969/j.issn.1001-5256.2019.10.009 |
| DatabaseName | ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials Proquest Central ProQuest One ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Health & Medical Complete (Alumni) ProQuest Health & Medical Collection Medical Database ProQuest Central Premium ProQuest One Academic ProQuest Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition Wanfang Data Journals - Hong Kong WANFANG Data Centre Wanfang Data Journals 万方数据期刊 - 香港版 China Online Journals (COJ) China Online Journals (COJ) |
| DatabaseTitle | Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) |
| DatabaseTitleList | Publicly Available Content Database |
| Database_xml | – sequence: 1 dbid: BENPR name: ProQuest Central url: http://www.proquest.com/pqcentral?accountid=15518 sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| DocumentTitle_FL | Minimally-invasive and multidisciplinary comprehensive diagnosis and treatment for HCC:2018 Guangzhou consensus |
| EISSN | 2097-3497 |
| EndPage | 2184 |
| ExternalDocumentID | lcgdbzz201910009 |
| GroupedDBID | -05 3V. 5XA 5XF 7X7 7XB 88E 8FI 8FJ 8FK 92F 92I ABDBF ABJNI ABUWG ACGFS ACUHS AFKRA ALMA_UNASSIGNED_HOLDINGS AZQEC BENPR CCEZO CCPQU CIEJG CW9 DWQXO EAD EAP EOJEC ESX FYUFA K9. M1P OBODZ OK1 PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI RNS TCJ TGQ U1G U5O 2B. 4A8 93N IPNFZ PSX RIG |
| ID | FETCH-LOGICAL-p1319-356e03fb7a2bee95eabc2c4055490bce666fe87d76553088dc614afa01fbef273 |
| IEDL.DBID | BENPR |
| ISSN | 1001-5256 |
| IngestDate | Thu May 29 04:06:08 EDT 2025 Tue Oct 07 07:21:21 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 10 |
| Keywords | 微创治疗 多学科综合治疗 肝细胞癌 共识 |
| Language | Chinese |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-p1319-356e03fb7a2bee95eabc2c4055490bce666fe87d76553088dc614afa01fbef273 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 |
| OpenAccessLink | https://www.proquest.com/docview/3240294144?pq-origsite=%requestingapplication%&accountid=15518 |
| PQID | 3240294144 |
| PQPubID | 7350069 |
| PageCount | 9 |
| ParticipantIDs | wanfang_journals_lcgdbzz201910009 proquest_journals_3240294144 |
| PublicationCentury | 2000 |
| PublicationDate | 2019-10-01 |
| PublicationDateYYYYMMDD | 2019-10-01 |
| PublicationDate_xml | – month: 10 year: 2019 text: 2019-10-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Changchun |
| PublicationPlace_xml | – name: Changchun |
| PublicationTitle | Linchuang gandanbing zazhi |
| PublicationTitle_FL | Journal of Clinical Hepatology |
| PublicationYear | 2019 |
| Publisher | Journal of Clinical Hepatology |
| Publisher_xml | – name: Journal of Clinical Hepatology |
| SSID | ssib051369456 ssib061082477 ssj0041983 ssib001103858 ssib053243598 ssib002264326 ssib038074677 |
| Score | 2.2075152 |
| Snippet | 摘要:中国绝大多数肝癌是乙型病毒性肝炎和肝硬化长期发展的结果,具有富血供、多中心起源特点,早期即可侵犯门静脉小分支并发生肝内转移。因此,肝癌发生之初即是一种局部器官... R735.7; 中国绝大多数肝癌是乙型病毒性肝炎和肝硬化长期发展的结果,具有富血供、多中心起源特点,早期即可侵犯门静脉小分支并发生肝内转移.因此,肝癌发生之初即是一种局部器... |
| SourceID | wanfang proquest |
| SourceType | Aggregation Database |
| StartPage | 2176 |
| SubjectTerms | Ablation Immunotherapy Liver cancer Medical diagnosis |
| Title | 肝细胞癌微创与多学科综合诊疗——2018广州共识 |
| URI | https://www.proquest.com/docview/3240294144 https://d.wanfangdata.com.cn/periodical/lcgdbzz201910009 |
| Volume | 35 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVEBS databaseName: Academic Search Ultimate customDbUrl: https://search.ebscohost.com/login.aspx?authtype=ip,shib&custid=s3936755&profile=ehost&defaultdb=asn eissn: 2097-3497 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0041983 issn: 1001-5256 databaseCode: ABDBF dateStart: 20130401 isFulltext: true titleUrlDefault: https://search.ebscohost.com/direct.asp?db=asn providerName: EBSCOhost – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources customDbUrl: eissn: 2097-3497 dateEnd: 99991231 omitProxy: true ssIdentifier: ssib053243598 issn: 1001-5256 databaseCode: M~E dateStart: 19850101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMUixME82NUnRtQC2hnVNTI3TdJMS0xJ1U80NzFMtEw0SDVLAp336mXmEmnhFmEYwMfjB9sKAllXCykRwQZ2SnwwaI9cHHRxnZGkCbP_bFxTqgm6NAs2uwq7QSIRerZBiCz5ijJmB1Qh0MhYLA6uTq19AEKKBYGiAcnoLaBspUgMGdPq6CdIBb6aGxmaWJojTZkyBrgAdeQfjA9seFkbgnZyQst8E2IWHLOkHdtJNga0JDgYVUL_Y0sxSPwucq_XgUqBlZZZ64JVlqM1b9vLEvLTEvHSkes5NkIEf2kBVcISkKCEGpqoMYQYOX-gUvAiDw4umuc93t71onvd8Zs_Tfeuedsx-sqPv6ZJZT9cue7584vPde55O6Hixvuv5tOmPGqYAEdABFk937n-6fd7T1o0v1reJMoS6uYY4e-hCr2HQLTAEbXEyNjVLNTBOSzJPNEpKTbU0TU1MSjZKBjb0gF1Lg6TkVGAHKC3VwjzF3Ax0BZGFRUoysMoHxreBYVpSahqweSTGwJKXn5cqwaBgmGZmmAwsVgzSzFJNEhONLEHHpRmamaaaGiYZJRuZSzLIwMIhHpqXiuMRMS_JoAgNG4RsTnJ6SlJVFSgwQVMVllL4jZBm4AIphSzHk2FgKSkqTZUFNitKkuQYmM0jzOUYWB2dXJzc5KApBwBZ5dVq |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMUixME82NUnRtQC2hnVNTI3TdJMS0xJ1U80NzFMtEw0SDVLAp336mXmEmnhFmEYwMeyD7YUBLauElYnggjolPxk0Rq4POjjOyNIE2P63LyjUBd0aBZpdhV2hkQi9WiHFFnzEGHRjh3dqZTmwC1ds6-kCjG9VIyM31xBnD13oLQO6BYagHTzGpmapBsZpSeaJRkmpqZamqYlJyUbJwHYMsOdkkJScCmzfp6VamKeYm4Fu2LGwSEkG1mhA7xgYpiWlpgFrf6C5zAysJsYmlsDOH6uTq19AEKJBYmiAcloMaNsqUoMJdNq7CdKBcqaGxmaWJojTbUyBvgYdsQfjA9s6FkbgnaOQusbE0NICsoXAwBDYpTQ142BQAfXDLc0s9bPApYgeXAq0jM1SD7ySDbU5zV6emJeWmJeOVK-6CTLwQxvECo6QFCzEwFSVIczA4Qud8hdhcHjRNPf57rYXzfOez-x5um_d047ZT3b0PV0y6-naZc-XT3y-e8_TCR0v1nc9nzb9UcMUIAI6wOLpzv1Pt8972rrxxfo2UYZQmkSIGANLXn5eqgSDgmGamWEysBgzSDNLNUlMNLIEHc9maGaaamqYZJRsZC7JIAMLh3ho3i2OR6Q0SQZFaNggZHOS01OSqqpAgQmaGrGUwm-EPAOnR4ivT7yPp5-3NAMXSBtkKaAMA0tJUWmqLLBJU5IkB003CgwJtE6qADqeEJo |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E8%82%9D%E7%BB%86%E8%83%9E%E7%99%8C%E5%BE%AE%E5%88%9B%E4%B8%8E%E5%A4%9A%E5%AD%A6%E7%A7%91%E7%BB%BC%E5%90%88%E8%AF%8A%E7%96%97%E2%80%94%E2%80%942018%E5%B9%BF%E5%B7%9E%E5%85%B1%E8%AF%86&rft.jtitle=Linchuang+gandanbing+zazhi&rft.au=%E4%BA%9A%E5%A4%AA%E5%BD%B1%E5%83%8F%E5%BC%95%E5%AF%BC%E4%B8%8B%E8%82%BF%E7%98%A4%E5%BE%AE%E5%88%9B%E6%B2%BB%E7%96%97%E5%8D%8F%E4%BC%9A%2C%E4%B8%AD%E5%9B%BD%E6%8A%97%E7%99%8C%E5%8D%8F%E4%BC%9A%E8%82%BF%E7%98%A4%E5%BE%AE%E5%88%9B%E6%B2%BB%E7%96%97%E4%B8%93%E4%B8%9A%E5%A7%94%E5%91%98%E4%BC%9A%EF%BC%8C%E4%BA%9A%E6%B4%B2%E8%82%BF%E7%98%A4%E6%B6%88%E8%9E%8D%E5%AD%A6%E4%BC%9A%EF%BC%882017%EF%BC%89&rft.date=2019-10-01&rft.pub=Journal+of+Clinical+Hepatology&rft.issn=1001-5256&rft.eissn=2097-3497&rft.volume=35&rft.issue=10&rft.spage=2176&rft_id=info:doi/10.3969%2Fj.issn.1001-5256.2019.10.009 |
| thumbnail_s | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.wanfangdata.com.cn%2Fimages%2FPeriodicalImages%2Flcgdbzz%2Flcgdbzz.jpg |