自身免疫性胰腺炎的病理学诊断

自身免疫性胰腺炎 (AIP) 是一种少见疾病，其诊断应基于对临床、影像学、血清学和病理学结果全面评估。目前将AIP分为两型：1型AIP被认为是与IgG4相关疾病的胰腺表现；2型AIP被视为与IgG4无关的胰腺特异性疾病。尽管1型和2型AIP的发病机制似乎不同，但二者的影像学表现相似，且均对类固醇激素有良好反应。本综述主要关注于AIP 2个亚型的病理组织学特征，尤其是内镜超声引导的细针穿刺活检组织的病理诊断难点，以提高AIP临床诊断的准确性。...

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Published inLinchuang gandanbing zazhi Vol. 40; no. 6; pp. 1100 - 1106
Main Author 孙柯
Format Journal Article
LanguageChinese
Published Changchun Journal of Clinical Hepatology 01.06.2024
浙江大学医学院附属第一医院病理科,杭州 310003
Subjects
Autoimmune Pancreatitis
Pathology
诊断
Biopsy
活组织检查
自身免疫性胰腺炎
Diagnosis
病理学
Online AccessGet full text
ISSN1001-5256
2097-3497
DOI10.12449/JCH240606

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Abstract 自身免疫性胰腺炎 (AIP) 是一种少见疾病，其诊断应基于对临床、影像学、血清学和病理学结果全面评估。目前将AIP分为两型：1型AIP被认为是与IgG4相关疾病的胰腺表现；2型AIP被视为与IgG4无关的胰腺特异性疾病。尽管1型和2型AIP的发病机制似乎不同，但二者的影像学表现相似，且均对类固醇激素有良好反应。本综述主要关注于AIP 2个亚型的病理组织学特征，尤其是内镜超声引导的细针穿刺活检组织的病理诊断难点，以提高AIP临床诊断的准确性。
AbstractList 自身免疫性胰腺炎 (AIP) 是一种少见疾病，其诊断应基于对临床、影像学、血清学和病理学结果全面评估。目前将AIP分为两型：1型AIP被认为是与IgG4相关疾病的胰腺表现；2型AIP被视为与IgG4无关的胰腺特异性疾病。尽管1型和2型AIP的发病机制似乎不同，但二者的影像学表现相似，且均对类固醇激素有良好反应。本综述主要关注于AIP 2个亚型的病理组织学特征，尤其是内镜超声引导的细针穿刺活检组织的病理诊断难点，以提高AIP临床诊断的准确性。
自身免疫性胰腺炎(AIP)是一种少见疾病,其诊断应基于对临床、影像学、血清学和病理学结果全面评估.目前将AIP分为两型:1型AIP被认为是与IgG4相关疾病的胰腺表现;2型AIP被视为与IgG4无关的胰腺特异性疾病.尽管1型和2型AIP的发病机制似乎不同,但二者的影像学表现相似,且均对类固醇激素有良好反应.本综述主要关注于AIP 2个亚型的病理组织学特征,尤其是内镜超声引导的细针穿刺活检组织的病理诊断难点,以提高AIP临床诊断的准确性.
Abstract_FL Autoimmune pancreatitis(AIP)is a rare disease,and its diagnosis should be made based on a comprehensive evaluation of clinical,radiological,serological,and pathological findings.At present,AIP is classified into two subtypes of type 1(identified as the pancreatic manifestation of IgG4-related disease)and type 2(identified as the pancreas-specific disorder independent of IgG4).Although type 1 and type 2 AIP seem to have different pathogeneses,they tend to have similar radiological findings and exhibit a good response to corticosteroid therapy.This article mainly reviews the histopathological features of the two subtypes of AIP,especially the diagnostic challenges encountered in the interpretation of specimens obtained through endoscopic ultrasound-guided fine needle aspiration/biopsy,to as to help pathologists enhance the accuracy of the diagnosis of AIP.
Author 孙柯
AuthorAffiliation 浙江大学医学院附属第一医院病理科,杭州 310003
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Issue 6
Keywords Autoimmune Pancreatitis
Pathology
诊断
Biopsy
活组织检查
自身免疫性胰腺炎
Diagnosis
病理学
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PublicationTitle_FL Journal of Clinical Hepatology
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浙江大学医学院附属第一医院病理科,杭州 310003
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Snippet 自身免疫性胰腺炎 (AIP) 是一种少见疾病，其诊断应基于对临床、影像学、血清学和病理学结果全面评估。目前将AIP分为两型：1型AIP被认为是与IgG4相关疾病的胰腺表现；2型AIP被...
自身免疫性胰腺炎(AIP)是一种少见疾病,其诊断应基于对临床、影像学、血清学和病理学结果全面评估.目前将AIP分为两型:1型AIP被认为是与IgG4相关疾病的胰腺表现;2型AIP被视为...
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