Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: (−)-usnic acid; 2D NMR analyses; 7α-acetoxy-6β-hydroxyroyleanone; adipogenesis; alkaline extraction; amphotericin B; anthocyanins; antibacterial activity; anticancer activity; antifungal activity; antimicrobial activity; antioxidant; antioxidants; antitumoral activity; Asphodelus ramosus; autophagy; bioactivities; bioavailability; biological activity; biosynthesis; Bursera graveolens; candidiasis; cellulite; Chagas disease; Chemistry; chemotaxonomy; collagenase inhibition; cytotoxicity; diabesity; dietary source; endoplasmic reticulum stress; ent-abietane; essential oil; ethosomes; Euphorbia; evernic acid; flavonoids; fructans; fructooligosaccharide; Garcinia indica; gel; herbal medicine; high-performance thin layer chromatography; human African trypanosomiasis; human American trypanosomiasis; Hymenocardia acida; IL-1β; infrared spectroscopy; inulin; ischemic stroke; isofuranodiene; kidney; kokum; lichen extracts; linarin; lipid accumulation; lipolysis; mass spectrometry; Mathematics and Science; melatonin; monoterpenes; mycosporine-like amino acids (MAAs); mycosporines; n/a; NAFLD; nanoencapsulation; nanoparticle; NF-ĸB; NMR spectroscopy; pharmacological activities; pharmacological activity; photoprotective compounds; phytochemistry; plant extract; Plectranthus; PLGA; Posidonia oceanica; propyl-propane-thiosulfinate; propyl-propane-thiosulfonate; Reference, Information and Interdisciplinary subjects; Research and information: general; root-tubers; royleanone; salazinic acid; Sambucus nigra L; secondary metabolites; skin compatibility; sleeping disease; Smyrnium olusatrum L; structure–activity relationship; terpenoids; Thai herbal compress; TNF-α; topical treatment; Trypanosoma; UV-absorbing compounds; vapor; vasorelaxation; wild mangosteen
• ISBN: 9783036568119; 3036568115; 9783036568102; 3036568107
• DOI: 10.3390/books978-3-0365-6810-2

For centuries, nature has been an inspirational source for the discovery of drugs used in modern medicine. Nowadays, natural-based treatments continue to be employed for primary health care, particularly playing a significant role in folk medicine. In addition, we are currently observing an increasing use of natural-products-based supplements from botanical and marine sources, making their standardization and scientific validation a priority to guarantee the safety of these products. Natural products and/or synthetic derivatives using their novel structures have also been of utmost importance in drug discovery and development in several clinical areas. After a period of discreditation and reduced investment, we are now witnessing a renewed interest from the pharmaceutical industry and scientific community due to the urgent need to develop new drugs. This reprint comprises 11 original and 6 review articles dedicated to plant and marine natural products research, contributing to the scientific validation of their use and opening new perspectives in drug discovery