위 말트(Mucosa-Associated Lymphoid Tissue) 림프종의 치료 후 장기성적: 단일기관 연구

• Published in: The Korean journal of helicobacter and upper gastrointestinal research Vol. 24; no. 1; pp. 64 - 71
• Format: Journal Article
• Language: English; Korean
• Published: Korean College of Helicobacter and Upper Gastrointestinal Research 01.03.2024; 대한상부위장관ㆍ헬리코박터학회
• Subjects: Original; 내과학
• ISSN: 1738-3331; 2671-826X
• DOI: 10.7704/kjhugr.2023.0051

Objectives: Few studies have reported long-term follow-up after treatment of gastric mucosaassociated lymphoid tissue (MALT) lymphoma. In this single-center study, we investigated longterm treatment outcomes in patients diagnosed with gastric MALT lymphoma. Methods: The study included 80 patients diagnosed with gastric MALT lymphoma, who were followed up at a single center between January 2005 and December 2019 after Helicobacter pylori eradication therapy, radiotherapy, or chemotherapy. We evaluated complete remission, improvement, or recurrence of the lesion. Follow-up over >60 months was classified as long-term follow-up, and the progression-free survival rate was recorded. Results: Following H. pylori eradication treatment, complete remission occurred in 85.9% (55/64) of H. pylori-positive and 50.0% (3/6) of H. pylorinegative patients. All patients with gastric MALT lymphoma who did not respond to H. pylori eradication therapy (100.0% [6/6]) achieved complete remission following administration of local radiotherapy. We observed no deaths on long-term follow-up (>60 months), and the progression-free survival was 101 months. Conclusions: In this study, patients with gastric MALT lymphoma showed excellent survival rates, progression-free survival, and prognosis on long-term follow-up. Prospective studies are warranted to determine the long-term prognosis of gastric MALT lymphoma after treatment. KCI Citation Count: 0