加味淸鼻飮이 흰쥐의 적출 동맥에 미치는 영향

The purpose of this research was to investigate the effects of supercritical fluid extract of Kamichungbieum (SFE) on the contraction of isolated rat aorta. The contractile force of rat aorta was measured with force displacement transducer under 1.5g loading tension. The contraction of aorta induced...

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Bibliographic Details
Published in동의생리병리학회지 Vol. 18; no. 4; pp. 1107 - 1110
Main Authors 은재순(Jae Soon Eun), 이동희(Dong Hee Lee), 한종현(Jong Hyun Han)
Format Journal Article
LanguageKorean
Published 한의병리학회 01.08.2004
Subjects
한의학
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ISSN1738-7698
2288-2529

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Summary:The purpose of this research was to investigate the effects of supercritical fluid extract of Kamichungbieum (SFE) on the contraction of isolated rat aorta. The contractile force of rat aorta was measured with force displacement transducer under 1.5g loading tension. The contraction of aorta induced by phenylephrine 0.1 μM was inhibited by SFE. The aorta relaxed by SFE was inhibited by the pretreatment of L-NNA, ODQ or indomethacin, respectively. These results indicate that SFE induce the relaxation of isolated aorta via activation of nitric oxide, cAMP and cyclooxygenase in epithelium cells. KCI Citation Count: 0
Bibliography:G704-000534.2004.18.4.022
ISSN:1738-7698
2288-2529