인삼에 함유된 페놀성 성분의 신경세포보호 및 항염증 효과

The six phenolic-compound (ascorbic acid, maltol, esculetin, p-coumaric acid, cinnamic acid, and quercetin) contents of Panax ginseng C.A. Meyer were determined in this study. The results showed that the ascorbic acid, cinnamic acid, and esculetin contents of Panax ginseng C.A. Meyer are higher than...

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Bibliographic Details
Published inJournal of ginseng research Vol. 33; no. 2; pp. 111 - 114
Main Authors 공연희(Yeon Hee Kong), 이영철(Young Chul Lee), 최상윤(Sang Yoon Choi)
Format Journal Article
LanguageKorean
Published 고려인삼학회 01.06.2009
Subjects
기타의약학
phenolic compound
nitric oxide
antioxidant
ginseng
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ISSN1226-8453
2093-4947

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Summary:The six phenolic-compound (ascorbic acid, maltol, esculetin, p-coumaric acid, cinnamic acid, and quercetin) contents of Panax ginseng C.A. Meyer were determined in this study. The results showed that the ascorbic acid, cinnamic acid, and esculetin contents of Panax ginseng C.A. Meyer are higher than those of the other ingredients. Among these compounds, ascorbic acid and cinnamic acid significantly inhibited LPS-induced nitric oxide production in the RAW 264.7 cells. Cinnamic acid also effectively inhibited the oxidative damages in the human neuroblastoma SH-SY5Y cells. Although this study examined the neuroprotective and anti-inflammatory activities using only one kind of cells, its results suggest that cinnamic acid potently contributes to the neuroprotective and anti-inflammatory properties of Panax ginseng C.A. Meyer. KCI Citation Count: 20
Bibliography:G704-000677.2009.33.2.004
ISSN:1226-8453
2093-4947