다양한 수면장애의 주기성사지운동증의 임상적 의의

• Published in: Sumyŏn--chŏngsin saengni Vol. 30; no. 1; pp. 9 - 12
• Main Author: 이소진
• Format: Journal Article
• Language: Korean
• Published: 대한수면의학회 30.06.2023; The Korean Academy of Sleep Medicine
• Subjects: 정신과학; Restless legs syndrome; Periodic limb movements during sleep (PLMS); 주기성사지운동장애·주기성사지운동증·폐쇄성수면무호흡증·하지불안증후군; Obstructive sleep apnea; Periodic limb movement disorder
• ISSN: 1225-7354; 2713-8631
• DOI: 10.14401/KASMED.2023.30.1.9

Periodic limb movements during sleep (PLMS) are prevalent in various sleep disorders, such as restless legs syndrome (RLS), periodic limb movements disorder, obstructive sleep apnea (OSA), REM sleep behavior disorder (RBD), and narcolepsy. PLMS has been hypothesized to be related to the decline of dopaminergic transmission. In RLS, PLMS is suggested to be related to iron deficiency and symptom severity. PLMD is a rare sleep disorder, and the role of PLMS in PLMD has not been clearly investigated yet. PLMS in OSA, which remain after proper PAP therapy, may need further management. The clinical relevance of PLMS in RBD and narcolepsy have not been investigated thoroughly and need further studies. Whether PLMS are to be considered as a mere symptom of individual sleep disorders or not can be elucidated through studies investigating the efficacy of therapeutic approaches to reduce PLMS in various sleep disorders.