영릉향으로부터 분리된 Foenumoside B의 부위별 함량비교 연구

• Published in: 생약학회지 Vol. 45; no. 1; pp. 88 - 92
• Main Authors: 엄영란(Young Ran Um), 목소연(So Youn Mok), 신재혁(Jae Hyuck Shin), 김슬기(Seul Ki Kim), 조병헌(Byoung Heon Cho), 조용백(Yong Baik Cho)
• Format: Journal Article
• Language: Korean
• Published: 한국생약학회 2014
• Subjects: 약학; Foenumoside B; Lysimachia foenum-graecum; HPLC
• ISSN: 0253-3073; 2288-9299

Lysimachia foenum-graecum (LF) has been used for home remedy of common cold and headache in China. Foenumoside B from LF has been reported for anti-obesity effects. We used foenumoside B as a marker for content evaluation of different parts of LF. Ethanol extract of LF was used for isolation of foenumoside B and purified further by column chromatography. The structure was identified as foenumoside B by interpretation of spectroscopic analysis, including $^1H$-, $^{13}C$-NMR and FT-ICR-MS. High-performance liquid chromatography (HPLC) method was used to compare the quantitative level of foenumoside B in different parts of LF. Foenumoside B contents in the leaf, stem, and aerial part showed significant differences. Contents of foenumoside B was detected highly in the leaf extracts. The results would be useful for efficient extraction of foenumoside B in LF.