세포독성 항암화학요법 유발 호중구 감소증에 대하여 복합 한방 치료를 병행하여 호전된 비소세포폐암 환자 1례

• Published in: 대한한방내과학회지 Vol. 46; no. 3; pp. 521 - 533
• Main Authors: 이민준, 최대준, 진수현, 유재환, Min-jun Lee, Dae-jun Choi, Su-hyun Chin, Jae-hwan Lew
• Format: Journal Article
• Language: Korean
• Published: 대한한방내과학회 01.06.2025
• Subjects: 한의학; Korean medicine; non small cell lung cancer; neutropenia; Ikgibohyeol-tang; chemotherapy
• ISSN: 1226-9174

Objectives: To report a case of non-small-cell lung cancer (NSCLC) with chemotherapy-induced neutropenia that improved following Korean medicine treatment. Methods: After developing neutropenia following the first cycle of cytotoxic chemotherapy, a patient with NSCLC received Korean medicine treatment including herbal medicine (Ikgibohyeol-tang) and acupuncture. To evaluate the therapeutic effect, changes in ANC levels and G-CSF dosage were assessed along with tumor response via computed tomography and magnetic resonance imaging and symptom changes using the FACT-L questionnaire. Results: After treatment, the patient showed improvement in the severity grade of neutropenia and lower G-CSF usage. The tumor size reduced, and the FACT-L score improved slightly. Conclusion: This case suggests that Korean medicine treatment may serve as a supportive therapy for managing chemotherapy-induced neutropenia in cancer patients.