하악골 골절에 대한 수술 시 예방적 항생제 사용과 술후 항생제 투여의 효율성

• Published in: Journal of the Korean Association of Oral and Maxillofacial Surgeons Vol. 35; no. 1; pp. 31 - 34
• Main Authors: 강상훈(Sang-Hoon Kang), 최영수(Young-Su Choi), 변인영(In-Young Byun), 김문기(Moon-Key Kim)
• Format: Journal Article
• Language: Korean
• Published: 대한구강악안면외과학회 28.02.2009; Korean Association Of Oral And Maxillofacial Surgeons
• Subjects: 치의학; Surgical site infection; Mandible fracture; Open reduction; Prophylactic antibiotics
• ISSN: 2234-7550; 2234-5930

Purpose: This study compared the frequency of postoperative infections in patients for a closed mandibular fracture with that without the postoperative antibiotic prophylaxis. Patients and Methods: 48 patients without any specific medical history were divided into two groups depending on whether or not antibiotics had been applied after the surgery. The 24 patients in group 1 received only a second-generation cephalosporin (Cefotetan®) intravenously from admission to immediate after the surgery. Likewise, 24 patients in group 2 received 1.0g of Cefotetan® twice daily longer than the third day after surgery. The mean (SD) duration of antibiotics administration after surgery was 6.9 (±3.56). The patients were evaluated after surgery for any postoperative infections according to the criteria: purulent drainage from a wound, spontaneous wound dehiscence accompanied by swelling, pain, and fever around the wound. Results: Postoperative infections were encountered in 2 out of 24 patients in group 1, who received antibiotic medication until shortly after surgery, and in 3 out of the 24 patients in group 2, in whom the medication was continued even after the surgery. There was no sig nificant difference in the incidence of postoperative infections between the two groups. Conclusion: From this study, postoperative use of antibiotics seems to be unnecessary with view of the little significance of the factors that could affect the wound infection. KCI Citation Count: 4