신이식 환자에서 발생한 무증상 파종성 크립토콕쿠스증 1예

• Published in: Kidney research and clinical practice Vol. 29; no. 2; pp. 310 - 314
• Main Authors: 전지민, Ji Min Jeon, 오준석, Joon Suk Oh, 김성민, Sung Min Kim, 손영기, Young Ki Son, 박용기, Yong Ki Park, 신용훈, Yong Hun Sin, 김중경, Joong Kyung Kim, 이일선, Il Seon Lee
• Format: Journal Article
• Language: Korean
• Published: 대한신장학회 30.03.2010
• Subjects: Cryptococcosis; Fungal infection; Kidney transplantation; 내과학
• ISSN: 2211-9132; 2211-9140

Cryptococcosis is recognized as one of the most important complications in an organ transplant recipient. Cryptococcosis occurs in 2.5-39% of renal transplant recipients. This infection generally presents as symptomatic disseminated disease with an accelerated clinical course, involves multiple sites including the central nervous system, lungs, and skin. And if diagnosis or treatment is delayed, the prognosis is generally poor. The asymptomatic infection is rare and there are no case reports of asymptomatic disseminated cryptococcosis after renal transplantation in Korea. We experienced a case of asymptomatic cryptococcal multi-organ infection detected incidentally in a 51-year-old male received a living related renal transplant 35 months earlier for end-stage renal disease due to diabetic nephropathy. We treated successfully with amphotericin B and fluconazole and hereby report this case with a review of the relevant literature.