만성 췌장염 치료의 최신 지견

• Published in: The Korean journal of gastroenterology Vol. 66; no. 3; pp. 144 - 149
• Main Authors: 박선미, 교신저자, Seon Mee Park
• Format: Journal Article
• Language: Korean
• Published: 대한소화기학회 30.09.2015
• Subjects: Antioxidants; chronic; Endoscopic retrograde cholangiopancreatography; Endosonography; Enzyme replacement therapy; Pancreatitis; 내과학
• ISSN: 1598-9992; 2233-6869

Treatment for chronic pancreatitis (CP) should be started early to prevent further pancreatic fibrosis and managed with a multidisciplinary approach to prevent complications and to maintain a good quality of life. The management strategies of CP can be divided into medical, endoscopic, and surgical treatment. The role of pancreatic enzymes and antioxidants for pain relief is not clearly defined, but their role in maintaining nutritional support by correcting exocrine insufficiency is well established. Endoscopic treatment is applied for resolution of pancreatic or bile duct strictures, clearance of pancreatic duct stones, and pseudocyst drainage. Endosonography-guided celiac plexus or celiac ganglia block for pain relief are known to be safe procedures but evidence for their effectiveness is still lacking. Surgery is commonly recommended when endoscopic therapy fails or there is suspicion of malignancy. New evidence-based guidelines for the management of CP are needed. (Korean J Gastroenterol 2015;66:144-149)