이차 병원 건강검진자의 바렛식도 유병률 및 분문부 장상피화생과의 비교 연구

• Published in: The Korean journal of gastroenterology Vol. 60; no. 4; pp. 219 - 223
• Main Authors: 최철영, Cheul Young Choi, 서승철, Seung Chul Suh, 박재석, Jae Serk Park, 이현정, Hyun Jeong Lee, 이종섭, Jong Sup Lee, 최효선, Hyo Sun Choi, 박현성, Hyun Sung Park, 홍승권, Seung Goun Hong
• Format: Journal Article
• Language: Korean
• Published: 대한소화기학회 30.10.2012
• Subjects: Barrett; Cardia; Free; Metaplasia; Prevalence; 내과학
• ISSN: 1598-9992; 2233-6869

Background/Aims: The purpose of this study was to estimate the prevalence of Barrett`s esophagus (BE) and its association with reflux esophagitis (RE) and peptic ulcer disease detected by free charge endoscopy which was covered by the National Health Insurance at a secondary care hospital, and to compare the results of the biopsy of BE with that of cardiac intestinal metaplasia (CIM). Methods: A total of 4,002 patients underwent endoscopy from March 2010 to December 2012. BE was diagnosed if there was histologically proven specialized intestinal metaplasia, and CIM was diagnosed if intestinal metaplasia was accompanied with chronic gastritis. Results: Four hundred twenty four patients underwent endoscopic biopsy, and the prevalence of BE was 1.0% (42/4,002), The mean age and the proportion of males in BE were significantly higher than those of the rest of study population, and BE had slight tendency related to RE than the rest of study population, CIM was observed in 34 patients and BE and CIM showed similar results, regarding age, sex and association with RE. The mean length of endoscopic Barrett`s mucosa of BE group was 9.2±5.1 mm, and it was similar to that of CIM. Conclusions: The prevalence of BE in the secondary care hospital was not low, and old age and male sex were significantly associated with BE. Because BE was observed in about 10% of biopsied patients and CIM was observed in a similar percentage with BE, the precise targeted biopsy is warranted and the biopsy method should be reestablished through the large prospective study of multiple secondary care hospitals.