원발성 사구체질환의 발생 빈도-단일병원분석

• Published in: Kidney research and clinical practice Vol. 30; no. 5; pp. 498 - 505
• Main Authors: 김기현, Ki Hyun Kim, 손영기, Young Ki Son, 이수미, Su Mi Lee, 안원석, Won Suk An, 김성은, Seong Eun Kim, 나서희, Seo Hee Rha
• Format: Journal Article
• Language: Korean
• Published: 대한신장학회 30.09.2011
• Subjects: Biopsy; Glomerulonephritis; Prevalenc; 내과학
• ISSN: 2211-9132; 2211-9140

Purpose: To evaluate the exact prevalence of primary glomerular diseases in Korea. Methods: We analyzed a retrospective cohort of biopsy proven 100 patients with primary glomerular disease in OO Hospital from April 1990 to March 2010. Results: Pathologic diagnosises of 100 cases were as follows: IgA nephropathy (IgAN) , 557 cases (50.6%), was the most common followed by 200 cases (18.1%) of minor glomerular abnormalities (MGA), 168 cases (15.2%) of focal segmental glomerulosclerosis (FSGS), 93 cases (8.0%) of membranous nephropathy (MN), 31 cases (2.8%) of membranoproliferative glomerulonephritis type I (MPGN), 17 cases (1.5%) of focal glomerulonephritis and 7 cases (0.6%) of diffuse mesangial proliferative glomerulonephritis (DMGN) in order. In idiopathic nephrotic syndrome, the most common pathologic diagnosis was minimal change nephrotic syndrome (MCNS) (40.2%), followed by FSGS (27.5%), MN (24.2%), MPGN (8.1%) and DMGN (0.5%). When the incidence rates between 1990-1992 and 2008-2010 were compared, IgAN and FSGS increased from 34.12.5 to 47.8%, 30.4%, but MCNS (from 33.3 to 6.5 %) decreased significantly Conclusion: IgAN was the most common primary glomerulonephritis. During the past 20 years, the prevalence of IgAN and FSGS were increased, while MCNS and MN were decreased.