소비자대상 직접 (DTC) 비만유전자 기반 정밀영양 (PNH)의 국내 현황

• Published in: Journal of nutrition and health Vol. 55; no. 6; pp. 601 - 616
• Main Authors: 김오연(Oh Yoen Kim), 이명숙(Myoungsook Lee), 이정희(Jounghee Lee), 손정민(Cheongmin Sohn), 윤미옥(Mi Ock Yoon)
• Format: Journal Article
• Language: Korean
• Published: 한국영양학회 2022
• Subjects: genome; technology; obesity; artificial intelligence; healthcare
• ISSN: 2288-3886; 2288-3959
• DOI: 10.4163/JNH.2022.55.6.601

In the era of the fourth industrial revolution technology, the inclusion of personalized nutrition for healthcare (PNH), when establishing a healthcare platform to prevent chronic diseases such as obesity, diabetes, cerebrovascular and cardiovascular disease, pulmonary disease, and inflammatory diseases, enhances the national competitiveness of global healthcare markets. Furthermore, since the government experienced COVID-19 and the population dead cross in 2020, as well as numerous health problems due to an increasing super-aged Korean society, there is an urgent need to secure, develop, and utilize PNH-related technologies. Three conditions are essential for the development of PNH technologies. These include the establishment of causality between obesity genome (genotype) and prevalence (phenotype) in Koreans, validation of clinical intervention research, and securing PNH-utilization technology (i.e., algorithm development, artificial intelligence-based platform, direct-to-customer [DTC]-based PNH, etc.). Therefore, a national control tower is required to establish appropriate PNH infrastructure (basic and clinical research, cultivation of PNH-related experts, etc.). The post-corona era will be aggressive in sharing data knowledge and developing related technologies, and Korea needs to actively participate in the large-scale global healthcare markets. This review provides the importance of scientific evidence based on a huge dataset, which is the primary prerequisite for the DTC obesity gene-based PNH technologies to be competitive in the healthcare market. Furthermore, based on comparing domestic and internationally approved DTC obese genes and the current status of Korean obesity genome-based PNH research, we intend to provide a direction to PNH planners (individuals and industries) for establishing scientific PNH guidelines for the prevention of obesity.