末梢性顔面神経麻痺の臨床症状と麻痺の回復

We investigated the relationship between clinical symptoms and recovery of patients with facial paralysis to identify the factors associated with recovery and to develop prognostic models. Clinical data were collected from 202 consecutive patients with peripheral facial paralysis. Outcome, which is...

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Published in理学療法学 Vol. 33; no. 7; pp. 386 - 393
Main Authors 濵野 俊明, 齋藤 幸広, 友井 貴子, 高関 じゅん, 齋藤 里美, 畠中 佳代子, 加藤 理恵, 内田 賢一
Format Journal Article
LanguageJapanese
Published 日本理学療法士学会 20.12.2006
Japanese Society of Physical Therapy
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ISSN0289-3770
2189-602X
DOI10.15063/rigaku.kj00004482363

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Summary:We investigated the relationship between clinical symptoms and recovery of patients with facial paralysis to identify the factors associated with recovery and to develop prognostic models. Clinical data were collected from 202 consecutive patients with peripheral facial paralysis. Outcome, which is recovery in 3 months or not, was analyzed with respective to characteristics (age, comorbidities), symptoms (cause of paralysis, first onset or recurrence, associated symptoms) and facial function,; 1) the lowest score after onset, 2) resting symmetry, 3) the number of present voluntary motions and 4) the number of improved items after 2 weeks. Age (over 40 years old), cause of paralysis (Hunt syndrome, tumor, trauma), present associated symptoms (otalgia, hearing loss, vertigo), and lower 4 facial functions are statistically significant risk. Facial function 1), 2) and 4) remained significant independent predictors in the logisitic regression model. The overall accuracy of this model to predict subject who did not recover in 3 months with a predicted probability of 0.5 or greater is 91.4%. The prognostic model consisted of the lowest score after onset, resting symmetry and the number of improved items after 2 weeks. The estimate of recovery from clinilal symptoms is important for clinical practice of physical therapy. 末梢性顔面神経麻痺の臨床症状から麻痺の回復に関連する要因及び予測モデルを検討した。対象患者202名の発症時年齢,麻痺の原因,背景疾患の有無,初発・再発,随伴症状の有無,顔面運動機能を調査した。顔面運動機能には40点法による評価から発症後最低点,安静時対称性スコア,表情運動9検査項日中収縮を認めた項目数(表情運動出現数),理学療法開始2週後に全10検査項目中改善した項目数(2週改善数)の4指標を設定した。発症から3ヶ月以内に回復した例を早期回復例,それ以外を遷延例として調査内容との関係を検討した。遷延のリスクが高いものは発症時年齢(40歳以上),麻痺の原因(Hunt症候群,腫瘍術後・外傷),随伴症状(耳痛,難聴,めまい),顔面運動機能4指標の成績不良であったが,随伴症状の主成分分析結果も含めた多重ロジスティック回帰分析では安静時対称性スコア,発症後最低点及び2週改善数が有意な説明変数であり,予測的中度は91.4%であった。3ヶ月以内の回復予測モデルは発症後1週経過時における安静時対称性と発症後最低点及び2週改善数で構成された。臨床症状からの麻痺回復予測は,麻痺患者に対する理学療法を進める上で有用な情報を与えるものと考える。
ISSN:0289-3770
2189-602X
DOI:10.15063/rigaku.kj00004482363